Anti-Peptic Ulcer Potential of a Polyherbal Mixture in Indomethacin-Induced Rat Model
نویسندگان
چکیده
منابع مشابه
A Direct Comparison of Anti-ulcer Effects of Coenzyme Q10 and Vitamin C on Indomethacin-induced Gastric Ulcer in Rat: A Controlled Experimental Study
Introduction: Indomethacin increases generation of mitochondrial reactive oxygen species (ROS) which have a crucial role in the indomethacin-induced gastric ulcer. Coenzyme Q10 has an antioxidant activity on mitochondria and cell membranes and protects lipids from oxidation and is essential for stabilizing biological membranes. Superoxide dismutase (SOD) acts as one of the defense mechanisms ag...
متن کاملAnti-ulcer Activity of Ethanol Extract of Parkia Speciosa against Indomethacin Induced Peptic Ulcer in Albino Rats
This study was performed to determine the anti-ulcer effects of ethanol extract of Parkia speciosa on Indomethacin induced peptic ulcer in Albino rats. Rats of female sex weighing between 150 g 200 g were used. Rats were divided into six groups with six rats in each group. Omeprazole (20 mg/kg) were used as a standard drug for this study. Parkia speciosa extract were given in three different do...
متن کاملSurvey of Protective Effect of Ghazzayaghi (Falcaria Vulgris) Extract Against Ethanol-Induced Peptic Ulcer in Rat
Purpose: Survey of protective effects of Ghazzayaghi (Falcaria vulgaris) extract against ethanol-induced peptic ulcer in rat. Materials and Methods: Thirty-five young male rats (NMRI); 200-250gr weight divided in to five groups (7 Rats/group), the groups were treated with: distilled water 10kg in Control negative group, 50mg/kg ranitidine in control positives group, and three case groups were ...
متن کاملEffects of Aloe vera, Camellia sinensis, Hibiscus sabdariffa and Sophora alopecuroides in Rat Model of Indomethacin-Induced Gastric Ulcer
Background: Evidences show that Aloe vera (A. vera), Camellia sinensis, Hibiscus sabdariffa and Sophora alopecuroides may prevent gastric ulcer induced by non-steroidal anti-inflammatory drugs (NSAIDs). Objective: To examine the protective potential of these plants against indomethacin-induced gastric ulcer in the rat. Methods: Saline, A. vera leaf gel powder and 70% alcoholic extracts of...
متن کاملHistopathologic evaluation of anti-ulcerogenic effect of montelukast in indomethacin-induced experimental ulcer model.
BACKGROUND/AIMS The effects of anti-ulcerogenic drugs are dependent on the increase in prostaglandin production and reduction in leukotriene production in the gastric mucosa. Montelukast is an anti-asthmatic drug, a selective reversible cysteinyl leukotriene D4 receptor antagonist. In this study, we aimed to evaluate the anti-ulcerogenic effect of montelukast and to investigate the relationship...
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ژورنال
عنوان ژورنال: Journal of Complementary Medicine & Alternative Healthcare
سال: 2018
ISSN: 2572-1232
DOI: 10.19080/jcmah.2018.06.555670